How Worry Affects The Brain

Worry affects the brain by triggering the body’s stress response, releasing hormones like cortisol and adrenaline that keep the mind in a constant state of alert. When worry becomes chronic, it overactivates the amygdala — the part of the brain responsible for fear and anxiety — and weakens the prefrontal cortex, which controls rational thinking and decision-making. This imbalance can make it harder to concentrate, regulate emotions, or think clearly. Over time, excessive worrying can even alter brain structure and function, increasing the risk of anxiety disorders, depression, and memory problems.